We build, advise, and invest in

purpose-built B2B health

tech startups.

based in
San Francisco

A studio dedicated to B2B health tech.

Pistole Labs is a venture studio that incubates, advises, and invests in B2B health tech startups.

In addition to capital, we bring a decade of experience building digital health solutions from the ground up and scaling them to millions of lives.

We've worked on various technologies at the intersection of behavioral science and chronic care:
• Virtual-first collaborative care
• Wearable biosensors
• Team-based health coaching
• Mobile digital phenotyping
• Prescription digital therapeutics

Our expertise lies in scaling these solutions through employer sales, benefit brokers, and strategic partnerships.

Seed Capital

We invest in early-stage startups that have demonstrated strong engagement, validated outcomes, and quantifiable ROI.

B2C to B2B

We help consumer startups develop and launch their B2B go-to-market motion — unlocking predictable, recurring revenue.

B2B Growth

We help teams accelerate their B2B sales motion, create new distribution channels, and scale via strategic partnerships.

Sequoia Capital
Google Ventures
Y Combinator
Andreessen Horowitz
First Round Capital
We love working with teams to transform a proven solution into a scalable, sustainable B2B business.
Oura
ŌURA
Wearable biosensor that measures sleep, stress, and heart health
Calm
Calm
#1 app for sleep, stress, and mindfulness
Big Health
Big Health
Prescription digital therapeutics for insomnia, anxiety, and depression
Galileo Health
Galileo Health
Fully bilingual health platform offering 24/7 virtual-first care
Omada Health
Omada Health
Team-based, integrative care for chronic conditions
Journey Clinical
Journey Clinical
Practice management software for psychedelic-assisted therapy
Anthropic
Anthropic
Safety-led next generation large language models
Bryte
Bryte
Multi-sensory, adaptive smart bed sleep system
Forta Health
Forta Health
AI-driven personalized therapy for autism spectrum disorder
Kindbody
Kindbody
Leading network of tech-enabled fertility clinics
Miga Health
Miga Health
Virtual collaborative care program for cardiometabolic health
Koko
Koko
AI-powered suicide identification and prevention
Motivo Health
Motivo Health
Virtual clinical supervision for behavioral health providers
Healthie
Healthie
Full-stack tech infrastructure for virtual-first care
We love connecting with awesome founders, potential partners, and fellow investors.

Our inbox is always open — feel free to leave your info below or connect with us on LinkedIn.
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